By Martin Stefan
Written by means of a workforce of specialists operating on the leading edge of this box, An Atlas of Schizophrenia describes schizophrenia's profound results on belief, knowing, communique, and social habit; its identifiable antecedents in early mind development and improvement; and its morphological info from structural mind imaging and autopsy experiences. It covers, with examples, the newest study advancements in neuropsychology, psychophysiology, and sensible imaging in addition to in vivo receptor imaging and different advances in psychopharmacology which are laying off new mild at the neurochemistry of schizophrenia.
Diagrams, tables, and figures bought via smooth imaging options mixed with examples of work from the Bethlem Royal sanatorium data and Museum illustrate the human in addition to the medical and psychiatric facets of the sickness. those positive factors offer you an entire photo of schizophrenia, its prognosis, and administration. With its blend of the newest examine and scientific facts and state of the art mind imaging suggestions, An Atlas of Schizophrenia offers a different visible presentation of the present knowing of the scientific gains, etiology, pathophysiology, and cures on hand.
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Extra info for Atlas of Schizophrenia
Neuropsychology of first-episode schizophrenia: initial characterization and clinical correlates. Am J Psychiatry 2000;157:549–59 Goldberg TE, Torrey EF, Bigelow LB, et al. Genetic risk of neuropsychological impairment in schizophrenia: a study of monozygotic twins discordant and concordant for the disorder. Schizophr Res 1995: 17:77–84 Jones P, Rodgers B, Murray R, Marmot M. Child development risk factors for adult schizophrenia in the British 1946 birth cohort. Lancet 1994;344: 1398–402 CHAPTER 4 Neurochemistry and pharmacotherapy INTRODUCTION efficacy of typical antipsychotic (neuroleptic) The discovery of the antipsychotic effects of chlorpromazine in the early 1950s heralded an era of effective pharmacological treatment for schizophrenia.
21)16. Childhood ‘schizoid’ personality traits may reflect deficits in cognition and in social behavior that are part of the disease process itself. Abnormalities of social behavior, movement and posture have also been reported (for example, in studies based on old home movies of affected and unaffected siblings). The antecedents of schizophrenia may therefore become identifiable long before the clinical onset of the illness. 20 Wisconsin card sort test (WCST) in monozygotic twins discordant for schizophrenia.
Lancet 1995;346:596–600 Spence SA, Brookes DJ, Hirsch SR, et al. A PET study of voluntary movement in schizophrenic patients experiencing passivity phenomena (delusions of alien control). Brain 1997;120:1997–2011 McGuire PK, Quested DJ, Spence SA, et al. Pathophysiology of ‘positive’ thought disorder in schizophrenia. Br J Psychiatry 1998;173:231–5J Frangou S, Sharma T, Alarcon G, et al. The Maudsley Family Study, II: Endogenous event-related potentials in familial schizophrenia. Schizophr Res 1997; 23:45–53 Gilvarry C, Takei N, Russell A, et al.
Atlas of Schizophrenia by Martin Stefan