By Kenneth L. Brigham, Mildred T. Stahlman
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Extra resources for Respiratory distress syndromes: molecules to man
Endotoxemia (E) in sheep alters specific lymphocyte subpopulations which correlate with lung pathophysiology. Fed. Proc. 46(3):992, 1987. 24. , Brigham, K. L. Human recombinant tumor necrosis factor alpha infusion mimics endotoxemia in awake sheep. J. Appl. Physiol. In press. 25. King, L. , Brigham, K. , Newman, J. H. Human recombinant interleukin 2 (IL2) infusion causes acute changes in lung vascular function in awake sheep. Physiologist. 30(4):212, 1987. 26. , Newman,J. , Brigham, K. L. Partial alteration of the development of oxygen toxicity by endotoxemia in awake sheep.
Brigham, K. , Meyrick, B. O. Endotoxin and lung injury: State of the art review. Am. Rev. Resp. Dis. 133:913-927, 1986. 5. Brigham, K. , Meyrick, B. Granulocyte dependent injury of pulmonary endothelium: A case of miscommunication? Tissue Cell. 16:137-155, 1984. 6. , Hoffman, L. , Brigham, K. L. Chemotaxis of granulocytes across bovine pulmonary artery intimal explants without endothelial cell injury. Tissue Cell. 16:1-16, 1984. 7. , Brigham, K. L. Acute effects of Escherichia coli endotoxin on the Page 28 pulmonary microcirculation of anesthetized sheep: Structure: function relationships.
For example: What is the relationship of the repair process to the character and extent of the acute injury? How do mechanical or pharmacological therapeutic interventions during the acute phase of lung injury affect the repair process? What are the critical host factors that determine whether an acutely injured lung will recover to normal or progress to chronic fibrosis or irreversible pulmonary hypertension? Page 26 Figure 2-10. ) Page 27 Figure 2-11. Pathology of the adult respiratory distress syndrome.
Respiratory distress syndromes: molecules to man by Kenneth L. Brigham, Mildred T. Stahlman